Products |Stellar KLH™

Sustainably Produced Stellar KLH™

  • Only KLH produced from domesticated sources

  • Controlled quality conditions, land-based aquaculture

  • Fully traceable

  • Non-destructive and environmentally sustainable extraction

  • GMP and research grades

Request a Quote

Stellar KLH™ is available to pharmaceutical companies, clinical research organizations as well as academic labs and individual researchers. Contact us to request a quote. Click on the tabs below for specific product information and specifications.

Stellar KLH™ Protein – Native High Molecular Weight – GMP Grade (Vialed)

Stellar’s native high molecular weight GMP-grade KLH developed for pre-clinical and early stage clinical research and development*

Description

This grade of Stellar KLH™ is intended for uses requiring current GMP standards as well as researchers interested in continuity of results across pre-clinical and clinical applications. Certificate of GMP Compliance included with all orders.
  • Potency – Induces robust primary and secondary IgM/IgG immune response without adjuvant. Stellar KLH is never lyophilized.
  • Consistency – Produced under controlled conditions from natural source to finished product.
  • Quality tested – Material has confirmed absence of enterovirus, Hepatitis A, Hepatitis B, Hepatitis C, Norwalk-like virus, and Rotavirus and low residual DNA. Low levels of endotoxin and other impurities
  • Sustainability – Produced only using environmentally sound methods from Stellar’s unique aquaculture production system.
  • Qualified Shippers – All orders are shipped express delivery in temperature-controlled packaging.

Additional information

Product High Molecular Weight Keyhole Limpet Hemocyanin
Product Code KLH-02NV
Packaging Clear Type I Borosilicate Glass V-Vial
Formulation Liquid in DPBS
Protein Concentration 2 mg/mL
Molecular Weight 4 to 8 MDa
Appearance Clear to slightly hazy blue liquid
Purity (SEC) ≥ 95%
pH 6.8 to 7.6
Endotoxin Level ≤ 7 Eu/mg protein
Storage Requirements 2° C to 8° C | Do not freeze
Source Controlled Aquaculture
* For manufacturing or processing in the preparation of a new drug or new animal drug limited by United States law to investigational use. STELLAR KLH PRODUCTS ARE EXPERIMENTAL IN NATURE AND ARE PROVIDED WITHOUT WARRANTY OF ANY SORT, EXPRESS OR IMPLIED, EXCEPT FOR THE SPECIFICATIONS OF THE CERTIFICATE OF ANALYSIS INCLUDED IN THE SHIPMENT.

Stellar KLH™ Protein – Native High Molecular Weight – Research Grade (Vialed)

Research grade Stellar KLH developed for academic and pre-clinical use as well as investigational research and development.

Description

This research grade of Stellar KLH™ is intended for non-GMP, non-clinical applications, including animal immunotoxicological studies.
  • Potency – Induces robust primary and secondary IgM/IgG immune response without adjuvant. Stellar KLH is never lyophilized.
  • Consistency – Produced under controlled conditions from natural source to finished product.
  • Sustainability – Produced only using environmentally sound methods from Stellar’s unique aquaculture production system.
  • Qualified Shippers – All orders are shipped express delivery in temperature-controlled packaging.

Additional information

Product High Molecular Weight Keyhole Limpet Hemocyanin
Product Code KLH-02NV
Packaging Clear Type I Borosilicate Glass V-Vial
Formulation Liquid in DPBS
Protein Concentration 2 mg/mL
Molecular Weight 4 to 8 MDa
Appearance Clear to slightly hazy blue liquid
pH 6.8 to 7.6
Storage Requirements 2° C to 8° C | Do not freeze
Source Controlled Aquaculture
STELLAR KLH PRODUCTS ARE EXPERIMENTAL IN NATURE AND ARE PROVIDED WITHOUT WARRANTY OF ANY SORT, EXPRESS OR IMPLIED, EXCEPT FOR THE SPECIFICATIONS OF THE CERTIFICATE OF ANALYSIS INCLUDED IN THE SHIPMENT.

Stellar KLH™ Protein – Native High Molecular Weight – GMP Grade (Bulk)

Out of Stock

Stellar’s native high molecular weight GMP-grade KLH developed for pre-clinical and early stage clinical research and development*

Description

This grade of Stellar KLH™ is intended for uses requiring current GMP standards as well as researchers interested in continuity of results across pre-clinical and clinical applications. Certificate of GMP Compliance included with all orders.
  • Potency – Induces robust primary and secondary IgM/IgG immune response without adjuvant. Stellar KLH is never lyophilized.
  • Consistency – Produced under controlled conditions from natural source to finished product.
  • Quality tested – Material has confirmed absence of enterovirus, Hepatitis A, Hepatitis B, Hepatitis C, Norwalk-like virus, and Rotavirus and low residual DNA. Low levels of endotoxin and other impurities
  • Sustainability – Produced only using environmentally sound methods from Stellar’s unique aquaculture production system.
  • Qualified Shippers – All orders are shipped express delivery in temperature-controlled packaging.

Additional information

Product High Molecular Weight Keyhole Limpet Hemocyanin
Product Code KLH-05N
Packaging Millipore Mobius Bag
Formulation Liquid in DPBS
Protein Concentration 4.5 to 5.5 mg/mL
Molecular Weight 4 to 8 MDa
Appearance Clear to slightly hazy blue liquid
Purity (SEC) ≥ 95%
pH 6.8 to 7.6
Endotoxin Level ≤ 7 Eu/mg protein
Storage Requirements 2° C to 8° C | Do not freeze
Source Controlled Aquaculture
* For manufacturing or processing in the preparation of a new drug or new animal drug limited by United States law to investigational use. STELLAR KLH PRODUCTS ARE EXPERIMENTAL IN NATURE AND ARE PROVIDED WITHOUT WARRANTY OF ANY SORT, EXPRESS OR IMPLIED, EXCEPT FOR THE SPECIFICATIONS OF THE CERTIFICATE OF ANALYSIS INCLUDED IN THE SHIPMENT.

Stellar KLH™ Protein – Subunit – GMP Grade (Bulk)

Out of Stock

Stellar’s native subunit GMP-grade KLH developed for pre-clinical and early stage clinical research and development*

Description

This grade of Stellar KLH™ is intended for uses requiring current GMP standards as well as researchers interested in continuity of results across pre-clinical and clinical applications. Certificate of GMP Compliance included with all orders.
  • Potency – Induces robust primary and secondary IgM/IgG immune response without adjuvant. Stellar KLH is never lyophilized.
  • Consistency – Produced under controlled conditions from natural source to finished product.
  • Quality tested – Material has confirmed absence of enterovirus, Hepatitis A, Hepatitis B, Hepatitis C, Norwalk-like virus, and Rotavirus and low residual DNA. Low levels of endotoxin and other impurities
  • Sustainability – Produced only using environmentally sound methods from Stellar’s unique aquaculture production system.
  • Qualified Shippers – All orders are shipped express delivery in temperature-controlled packaging.

Additional information

Product Subunit Weight Keyhole Limpet Hemocyanin
Product Code KLH-20M
Packaging Millipore Mobius Bag
Formulation Liquid in water for injection
Protein Concentration 18 to 22 mg/mL
Molecular Weight > 400 – 600 kDa
Appearance Clear to slightly hazy blue liquid
Purity (SEC) ≥ 90%
pH 6.9 to 7.9
Endotoxin Level ≤ 5 Eu/mg protein
Storage Requirements 2° C to 8° C | Do not freeze
Source Controlled Aquaculture
  * For manufacturing or processing in the preparation of a new drug or new animal drug limited by United States law to investigational use. STELLAR KLH PRODUCTS ARE EXPERIMENTAL IN NATURE AND ARE PROVIDED WITHOUT WARRANTY OF ANY SORT, EXPRESS OR IMPLIED, EXCEPT FOR THE SPECIFICATIONS OF THE CERTIFICATE OF ANALYSIS INCLUDED IN THE SHIPMENT.

Stellar KLH™ Protein – Subunit – Research Grade (Bulk)

Out of Stock

Research grade Stellar KLH developed for academic and pre-clinical use as well as investigational research and development.

Description

This research grade of Stellar KLH™ is intended for non-GMP, non-clinical applications, including animal immunotoxicological studies.
  • Potency – Induces robust primary and secondary IgM/IgG immune response without adjuvant. Stellar KLH is never lyophilized.
  • Consistency – Produced under controlled conditions from natural source to finished product.
  • Sustainability – Produced only using environmentally sound methods from Stellar’s unique aquaculture production system.
  • Qualified Shippers – All orders are shipped express delivery in temperature-controlled packaging.

Additional information

Product Subunit Keyhole Limpet Hemocyanin
Product Code KLH-20MR
Packaging Millipore Mobius Bag
Formulation Liquid in water for injection
Protein Concentration 18 to 22 mg/mL
Molecular Weight > 400 – 600 kDa
Appearance Clear to slightly hazy blue liquid
pH 6.9 to 7.9
Storage Requirements 2° C to 8° C | Do not freeze
Source Controlled Aquaculture
STELLAR KLH PRODUCTS ARE EXPERIMENTAL IN NATURE AND ARE PROVIDED WITHOUT WARRANTY OF ANY SORT, EXPRESS OR IMPLIED, EXCEPT FOR THE SPECIFICATIONS OF THE CERTIFICATE OF ANALYSIS INCLUDED IN THE SHIPMENT.
Unless otherwise expressly agreed to in writing, all sales are subject to Stellar’s Purchase Terms and Conditions.

The Stellar KLH™ Advantage

Stellar KLH protein is sourced from limpets raised in a safe, controlled habitats. By relying on our domesticated sources, we protect scarce, wild populations from being depleted.  And, you receive a consistent product cultured under known conditions.

Additional Resources

  1. Herscowitz, Harold, and Stavitsky. Immunochemical and immunogenic properties of a purified keyhole limpet haemocyanin. Immunol. 1972; 22: 51-61. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1408198/
  2. Miller, Curtsinger, Berthold, Malvey, Bliss, Le, Fautsch, Dudek, Blazar and Panoskaltsis-Mortari. Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation. Clin. Immunol. 2005;117: 144-151. http://www.klhsite.org/klh-publications/diminished-neo-antigen-response-to-keyhole-limpet-hemocyanin.html
  3. Lebrec, Hock, Sundsmo, Mytych, Chow, Carlock, Joubert. T-cell Dependent Antibody Responses in the rat: Forms and sources of keyhole limpet hemocyanin matter. Poster presentation, Annual Meeting of the Society of Toxicology (SOT) 2013. http://www.klhsite.org/klh-publications/t-cell-dependent-antibody-responses-in-the-rat-forms-and-sou.html
  4. Keyhole Limpet Hemocyanin Knowledge Base. www.klhsite.org